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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNRD2
All Species:
16.97
Human Site:
T338
Identified Species:
24.89
UniProt:
Q9NNW7
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NNW7
NP_006431.2
524
56507
T338
G
V
D
T
S
P
D
T
Q
K
I
L
V
D
S
Chimpanzee
Pan troglodytes
XP_001166615
481
51948
F308
G
K
E
D
T
G
T
F
D
T
V
L
W
A
I
Rhesus Macaque
Macaca mulatta
NP_001152971
524
56314
T338
G
V
D
T
S
P
D
T
Q
K
I
L
V
D
S
Dog
Lupus familis
XP_850181
509
55065
S325
G
V
N
T
N
P
N
S
Q
K
I
L
V
N
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLT4
524
56434
N338
G
I
S
T
N
P
K
N
Q
K
I
I
V
D
A
Rat
Rattus norvegicus
Q9Z0J5
526
56406
N340
G
V
N
T
N
P
K
N
Q
K
I
I
V
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001116163
518
56137
T332
G
V
K
T
N
S
E
T
G
K
I
I
V
D
A
Frog
Xenopus laevis
NP_001080052
504
54666
T318
G
V
K
I
K
P
E
T
G
K
I
I
V
D
A
Zebra Danio
Brachydanio rerio
NP_898895
602
65949
N413
D
K
A
G
V
K
I
N
E
K
N
G
K
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91938
596
64304
K412
G
V
T
V
Q
K
D
K
I
P
V
D
S
Q
E
Honey Bee
Apis mellifera
NP_001171496
537
59227
A353
L
K
L
V
P
E
T
A
K
I
D
A
I
D
E
Nematode Worm
Caenorhab. elegans
Q17745
667
74094
T471
T
D
D
V
G
L
T
T
I
G
V
E
R
A
K
Sea Urchin
Strong. purpuratus
XP_797733
490
53044
K309
V
Q
L
S
E
G
G
K
V
M
G
S
N
E
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48641
499
53852
Q316
A
V
G
V
E
L
D
Q
A
G
A
V
K
V
D
Baker's Yeast
Sacchar. cerevisiae
P41921
483
53422
H298
W
T
I
G
R
K
S
H
L
G
M
G
S
E
N
Red Bread Mold
Neurospora crassa
Q873E8
468
50294
G297
G
V
K
T
N
E
K
G
Y
I
E
V
D
E
Y
Conservation
Percent
Protein Identity:
100
91
98.2
83.2
N.A.
84.5
82.6
N.A.
N.A.
72.9
68.6
47
N.A.
48.9
53
40.7
55.7
Protein Similarity:
100
91.2
99
91.4
N.A.
91.5
90.8
N.A.
N.A.
86
82.2
62.2
N.A.
62.4
68.5
56.2
69.8
P-Site Identity:
100
13.3
100
60
N.A.
53.3
60
N.A.
N.A.
53.3
53.3
6.6
N.A.
20
6.6
13.3
0
P-Site Similarity:
100
33.3
100
100
N.A.
80
86.6
N.A.
N.A.
80
73.3
13.3
N.A.
26.6
20
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
32.8
34.7
Protein Similarity:
N.A.
N.A.
N.A.
51.7
53
52.4
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
20
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
0
0
0
7
7
0
7
7
0
13
32
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
19
7
0
0
25
0
7
0
7
7
7
44
7
% D
% Glu:
0
0
7
0
13
13
13
0
7
0
7
7
0
19
13
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
63
0
7
13
7
13
7
7
13
19
7
13
0
0
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
7
7
7
0
0
7
0
13
13
44
25
7
0
7
% I
% Lys:
0
19
19
0
7
19
19
13
7
50
0
0
13
0
7
% K
% Leu:
7
0
13
0
0
13
0
0
7
0
0
25
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% M
% Asn:
0
0
13
0
32
0
7
19
0
0
7
0
7
7
7
% N
% Pro:
0
0
0
0
7
38
0
0
0
7
0
0
0
0
7
% P
% Gln:
0
7
0
0
7
0
0
7
32
0
0
0
0
7
7
% Q
% Arg:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% R
% Ser:
0
0
7
7
13
7
7
7
0
0
0
7
13
0
13
% S
% Thr:
7
7
7
44
7
0
19
32
0
7
0
0
0
0
0
% T
% Val:
7
57
0
25
7
0
0
0
7
0
19
13
44
13
0
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _